New Blood Test Can Detect Head And Neck Cancer 10 Years Early

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Scientists have devised a new blood test that can help identify head and neck cancers up to 10 years before the symptoms appear. Researchers from Harvard-affiliated Mass General Brigham published their findings in the Journal of the National Cancer Institute, highlighting that by catching cancers early, patients may experience higher treatment success and require a less intense regimen.

Human papillomavirus (HPV) is responsible for an estimated 70 per cent of head and neck cancers in the US, making it the most common cancer caused by the virus, the study showed. Despite this, there is no screening test for HPV-associated head and neck cancers.

To address the issue, the researchers developed a novel liquid biopsy test, called HPV-DeepSeek, that can detect HPV-related head and neck cancers early, before symptoms develop.

"Our study shows for the first time that we can accurately detect HPV-associated cancers in asymptomatic individuals many years before they are ever diagnosed with cancer," said lead study author Daniel L Faden, assistant professor of otolaryngology–head and neck surgery at Harvard Medical School.

"By the time patients enter our clinics with symptoms from the cancer, they require treatments that cause significant, life-long side effects. We hope tools like HPV-DeepSeek will allow us to catch these cancers at their very earliest stages, which ultimately can improve patient outcomes and quality of life."

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